When adventurous pets Chance, Shadow and Sassy are accidentally separated from their vacationing owners, they’re left to fend for themselves on the mean streets of San Francisco, in search for the “golden bridge” that will take them home.

Ping is a chihuahua rescued from the pound by nearsighted Ethel, who thinks he’s a cat. When a pair of bumbling thieves try to break into Ethel’s house to steal the money they think she has stashed away, only Ping can foil their plans.

The on-going war between the canine and feline species is put on hold when they join forces to thwart a rogue cat spy with her own sinister plans for conquest.